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Radiofrequency versus microwave ablation for treatment of the lung tumours: LUMIRA (lung microwave radiofrequency) randomized trial

Data pubblicazione

2017/5

Editore

Springer US

Autori

M Macchi, MP Belfiore, C Floridi, N Serra, G Belfiore, L Carmignani, RF Grasso, E Mazza, C Pusceddu, Luca Brunese, G Carrafiello

Abstract

The LUMIRA trial evaluated the effectiveness of radiofrequency (RFA) and microwave ablation (MWA) in lung tumours ablation and defining more precisely their fields of application. It is a controlled prospective multi-centre random trial with 1:1 randomization. Fifty-two patients in stage IV disease (15 females and 37 males, mean age 69 y.o., range 40–87) were included. We randomized the patients in two different subgroups: MWA group and RFA group. For each group, we evaluated the technical and clinical success, the overall survival and complication rate. Inter-group difference was compared using Chi-square test or Fisher’s exact test for categorical variables and one-way ANOVA test for continuous variables. For RFA group, there was a significant reduction in tumour size only between 6 and 12 months (p value = 0.0014). For MWA group, there was a significant reduction in tumour size between 6 and …

Pagine

1-10

Contatti

Dott. Claudio Pusceddu – Mater Olbia Email: clapusceddu@gmail.com Telefono: 380 30 89 094